Crepiness & elasticity loss
Brown spots & sun damage
Fine lines & wrinkles
Dullness & uneven tone
Dryness & crepey texture
Key Ingredients:
Dipalmitoyl hydroxyproline
Stabilized vitamin C & resveratrol
Disodium acetyl glucosamine phosphate
Citrulline & Watermelon extract Red marine algae extract Silver ear mushroom extract Hydrolyzed hyaluronic acid Eight-plant antioxidant shield Caffeine Full amino acid complex: Arginine, glycine, alanine, serine, valine, proline, threonine, isoleucine, histidine, and phenylalanine Olive-derived lipids, jojoba esters & squalane The Science Behind the Formula: The neck and décolletage present a clinical challenge that most skincare brands simply repurpose face cream to address. Dr. Alexiades did not. This formula was built around the specific biology of neck skin — its thinner structure, its elasticity dependence, its history of cumulative UV damage, and its unique need for both barrier repair and active treatment simultaneously. Dipalmitoyl hydroxyproline is the kind of targeted, mechanism-specific active that only appears in a formula when the formulator understood exactly what problem they were solving for. Results: Immediately: Visibly more hydrated, smoother, and more supple neck and décolletage skin with a nourished, revived feel. With Regular Use: Measurably improved elasticity and firmness, visibly reduced crepiness, brightened brown spots, more even skin tone, softened fine lines and wrinkles, and a sustained luminosity that reflects skin that has been genuinely treated — not just moisturized. How to Use: Apply to neck and décolletage morning and evening after serum, using upward strokes from the chest to the jawline. For the décolletage, smooth outward from the sternum. Use consistently — the elasticity and pigmentation changes this formula targets are built over time, and the results compound with continued use. 3.4 oz./ 100 mL
Size Reference for Macrene Actives Treatment, 3.4 oz.
Available Sizes:

























