ABOUT THE BRAND
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DR. MACRENE actives was founded by Dr. Macrene Alexiades, MD, PhD, a dual board-certified dermatologist and scientist whose decades of clinical expertise and scientific innovation inform every formulation. Grounded in cutting-edge research and earth conscious practices, the brand combines advanced delivery technologies with potent, multi-active complexes to visibly address the signs of aging while supporting long-term skin health. Each formula is meticulously crafted with clean, nontoxic, plant-based ingredients, incorporating certified organic botanicals whenever possible. Cruelty-free and thoughtfully formulated without common irritants, DR. MACRENE actives represents the intersection of clinical efficacy and uncompromising ingredient integrity-delivering sophisticated, high-performance skincare designed to meet the highest standards of both science and luxury.
WHAT IT IS
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A high-performance tinted lip filler treatment that delivers buildable, natural-looking color while treating lips with a 20+ active complex. Formulated to mimic volumizing and smoothing effects of injectable filler without needles, it combines peptides, microencapsulated hyaluronic acids for sustained hydration, ceramides to support the moisture barrier, and antioxidants plus plant oils to protect and nourish. Pigments are clean, non-toxic and plant-based.
WHAT IT DOES
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Sheer gloss provides hydrating, smoothing, to visibly plump lips. Regular use helps reduce the appearance of fine lines, improve lip definition, and support a softer, more youthful lip surface. Does not provide immediate swelling effect via increased blood flow, clinically proven to plump over time with continued use of product.
HOW TO USE IT
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Shake well and use the applicator wand to blend the formula. Apply a small dab to the center of the upper and lower lips and blend outward, at least twice daily or as desired. Can also be applied above the lip line to soften the appearance of fine lines. *Formula may separate as it does not contain toxic binders.
CLINICAL RESULTS
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From an 8-week trial of 27 subjects, ages 37-68. 100% said lips felt more moisturized; 100% said lips looked smoother; 100%; said lips felt softer; Proven to improve the look of lip volume.
.17 oz
Free of Gluten, Parabens, Phthalates, Sulfates, Fragrance, Acrylate, Propylene-Glycol, Mineral Oil, Petrolatum, Animal Byproducts, Mica, Talc, Silicone.
Lip Filler: Microencapsulated Hyaluronic Acid Anti-Wrinkle: Dipalmitoyl hydroxyproline Peptide Anti-Chap: Coconut Oil, Ceramides, Shea Butter, Squalane, Plant Octyl Lipids Anti-Oxidants: Vitamin E, Rosemary Extract, and Echium plantagineum Emollient / Mo
USDA Certified Organic Ingredients - Plant-Based - Cruelty-Free - Non-Comedogenic - Packaged in Glass - Made in USA
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Glass tube with doe foot applicator
Made in USA
Web ID: 6382463
Style Variants
Available Colors: Clear
Size Reference for Dr. MACRENE actives Collection, 0.17 oz.
Available Sizes:










